pubmed-article:7746322 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C0206588 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C0012591 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C1879748 | lld:lifeskim |
pubmed-article:7746322 | lifeskim:mentions | umls-concept:C1706853 | lld:lifeskim |
pubmed-article:7746322 | pubmed:issue | 6528 | lld:pubmed |
pubmed-article:7746322 | pubmed:dateCreated | 1995-6-14 | lld:pubmed |
pubmed-article:7746322 | pubmed:abstractText | Nuclear receptor heterodimers recognize response elements composed of two direct repeats of the consensus sequence 5'-AGGTCA-3' separated by one to five base pairs. The 1.9 A crystal structure of the complex formed by the DNA-binding domains of the 9-cis retinoic acid receptor and thyroid hormone receptor bound to a thyroid-response element shows that the subunits interact through a DNA-supported interface involving the carboxy-terminal extension of the DNA-binding domain of the thyroid hormone receptor. The stereochemistry suggests a mechanism by which heterodimers recognize the inter-half-site spacing between direct repeats. | lld:pubmed |
pubmed-article:7746322 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7746322 | pubmed:language | eng | lld:pubmed |
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pubmed-article:7746322 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:7746322 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7746322 | pubmed:month | May | lld:pubmed |
pubmed-article:7746322 | pubmed:issn | 0028-0836 | lld:pubmed |
pubmed-article:7746322 | pubmed:author | pubmed-author:EvansR MRM | lld:pubmed |
pubmed-article:7746322 | pubmed:author | pubmed-author:SiglerP BPB | lld:pubmed |
pubmed-article:7746322 | pubmed:author | pubmed-author:RastinejadFF | lld:pubmed |
pubmed-article:7746322 | pubmed:author | pubmed-author:PerlmannTT | lld:pubmed |
pubmed-article:7746322 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7746322 | pubmed:day | 18 | lld:pubmed |
pubmed-article:7746322 | pubmed:volume | 375 | lld:pubmed |
pubmed-article:7746322 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7746322 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7746322 | pubmed:pagination | 203-11 | lld:pubmed |
pubmed-article:7746322 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:7746322 | pubmed:year | 1995 | lld:pubmed |
pubmed-article:7746322 | pubmed:articleTitle | Structural determinants of nuclear receptor assembly on DNA direct repeats. | lld:pubmed |
pubmed-article:7746322 | pubmed:affiliation | Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, USA. | lld:pubmed |
pubmed-article:7746322 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7746322 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:7746322 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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