7743757

Source:http://linkedlifedata.com/resource/pubmed/id/7743757

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007226, umls-concept:C0009248, umls-concept:C0013331, umls-concept:C0026538, umls-concept:C0026565, umls-concept:C0030705, umls-concept:C0086343, umls-concept:C0332307
pubmed:issue	2
pubmed:dateCreated	1995-6-9
pubmed:abstractText	A historical cohort study was performed to assess cardiovascular morbidity and mortality in Type 2 (non-insulin-dependent) diabetic patients. The data were collected from 1967 to 1989 in four Dutch general practices performing the Continuous Morbidity Registration Nijmegen. Each newly diagnosed Type 2 diabetic patient fulfilling the WHO criteria (n = 265) was matched to a control patient for practice, sex, age, and social class. Inclusion started in 1967, the first year of the still ongoing, Continuous Morbidity Registration Nijmegen. On average, a follow-up of 6.8 years (range 1 month-22 years) was realized. Compared to the non-diabetic control patients, the Type 2 diabetic patients showed higher cardiovascular morbidity (risk ratio 1.76, 95% CI 1.34-2.30) and a higher mortality rate (risk ratio 1.54, 95% CI 1.07-2.23). Mortality after 10 years was 36% vs 20% (p < 0.01), the median survival time 16 years vs 19 years. The cumulative survival rates were significantly different (p < 0.01) between patients and controls in the age group 65-74 years. The higher mortality in Type 2 diabetic patients was completely due to an excess of cardiovascular death (risk ratio 2.05, 95% CI 1.24-3.37).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8500858
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0742-3071
pubmed:author	pubmed-author:de GrauwW JWJ, pubmed-author:van WeelCC, pubmed-author:van de LisdonkE HEH, pubmed-author:van den HoogenH JHJ
pubmed:issnType	Print
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	117-22
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:7743757-Aged, pubmed-meshheading:7743757-Cardiovascular Diseases, pubmed-meshheading:7743757-Cohort Studies, pubmed-meshheading:7743757-Diabetes Mellitus, Type 1, pubmed-meshheading:7743757-Diabetes Mellitus, Type 2, pubmed-meshheading:7743757-Diabetic Angiopathies, pubmed-meshheading:7743757-Family Practice, pubmed-meshheading:7743757-Female, pubmed-meshheading:7743757-Follow-Up Studies, pubmed-meshheading:7743757-Humans, pubmed-meshheading:7743757-Male, pubmed-meshheading:7743757-Middle Aged, pubmed-meshheading:7743757-Morbidity, pubmed-meshheading:7743757-Netherlands, pubmed-meshheading:7743757-Registries, pubmed-meshheading:7743757-Retrospective Studies, pubmed-meshheading:7743757-Sex Characteristics, pubmed-meshheading:7743757-Social Class, pubmed-meshheading:7743757-Time Factors
pubmed:year	1995
pubmed:articleTitle	Cardiovascular morbidity and mortality in type 2 diabetic patients: a 22-year historical cohort study in Dutch general practice.
pubmed:affiliation	Department of General Practice and Social Medicine, University of Nijmegen, The Netherlands.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't