Linked Life Data

7741270

Source:http://linkedlifedata.com/resource/pubmed/id/7741270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-6-2
pubmed:abstractText
The epithelium associated with the lymphoid follicles of Peyer's patches differs from the villi epithelium by the presence of M cells. The main function of these cells is to take up antigens (inert material, viruses and bacteria) from the intestinal lumen. The M cells are able to internalize various different gram-negative bacteria. In order to show the M cells ability to interact and take up a gram-positive bacterium, we exposed rabbit Peyer's patches to Streptococcus pneumoniae R36a. Using the isolated ileal loop technique, Peyer's patches were incubated with a bacterial suspension for varying periods (15, 30, 60, 100 minutes). The bacteria were found outside and inside the M cells. The internalized streptococci could be found in the M cell cytoplasm, in the cytoplasmic "pockets" and inside the intraepithelial lymphoid cells. The finding of internalized bacteria with their damaged walls suggests the possibility that M cells are able to modify internalized antigens in the same way as the antigen presenting cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0940-9602
pubmed:author
pubmed:issnType
Print
pubmed:volume
177
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
119-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Uptake of a gram-positive bacterium (Streptococcus pneumoniae R36a) by the M cells of rabbit Peyer's patches.
pubmed:affiliation
Institute of Human Anatomy, University of Siena, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't