Linked Life Data

7740762

Source:http://linkedlifedata.com/resource/pubmed/id/7740762

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1995-6-7
pubmed:abstractText
Early detection of swine influenza A outbreaks is essential to understand the true cause and effect relationship that exists between this disease and other serious respiratory or herd health problems. Enzyme-linked immunosorbent assays (ELISAs) for the early detection of H1N1 subtype specific serum IgM, IgG and secretory IgA were compared to direct virus detection in in embryonated eggs. Elevated levels of H1 hemagglutinin (HA) specific IgM and IgG were detected as early as 3 days post experimental infection with a field strain of swine influenza A (H1N1). Influenza specific IgA in nasal mucous samples was detected on day 4 post infection (PI). This compared favorably with egg inoculation methods which detected virus 2-4 days PI. Identification of elevated H1 HA specific IgM in test herds could signify a recent influenza outbreak. Alternatively, ELISA analysis of nasal mucous samples for H1 HA specific IgA could provide a noninvasive method of obtaining similar information on the influenza specific immune status of the herd.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0378-1135
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Class specific antibody response to influenza A H1N1 infection in swine.
pubmed:affiliation
Department of Veterinary PathoBiology, College of Veterinary Medicine, University of Minnesota, St. Paul, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't