Linked Life Data

7736552

Source:http://linkedlifedata.com/resource/pubmed/id/7736552

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-6-8
pubmed:abstractText
Changing patterns of glycan distribution are described in porcine placentae at 15, 19, 26, 43, 58, 69 and 109 days gestation, using a carefully selected panel of lectins that allowed partial analysis of saccharide classes and sequences. The lectins used were from Galanthus nivalis, Pisum sativum, Phaseolus vulgaris (leukohaemagglutinin), Triticum vulgaris, Tetragonolobus purpureus, Ulex europaeus-1, Arachis hypogaea, Erythrina cristagalli, Glycine max, Maclura pomifera, Wisteria floribunda, Dolichos biflorus, Maackia amurensis, Sambucus nigra and Limax flavus. During the course of gestation the trophoblast developed from a smooth to a deeply folded membrane, while enlarging fetal and maternal capillaries grew closer to each other. The fetomaternal interface expressed many classes of saccharide, both O- and N-linked, but failed to bind DBA, MAA and SNA. Many granules were present in the maternal epithelium, and a striking feature was the appearance of staining with DBA and UEA-1 by day 43. This stage of pregnancy was also associated with changes in trophoblast glycan expression, with a diminution in staining intensity of AHA, MPA and LTA, but an increased intensity with ECA, SBA and WFA. Changes in lectin binding throughout gestation are correlated with previous ultrastructural findings and their relevance to the immunological and functional aspects of pregnancy is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0302-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
279
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Changes in glycan distribution within the porcine interhaemal barrier during gestation.
pubmed:affiliation
Department of Pathological Sciences, University of Manchester, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't