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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-6-7
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pubmed:abstractText |
The hedonic properties of delta-9-tetrahydrocannabinol (THC) were assessed in place and taste conditioning paradigms in both Lewis and Sprague-Dawley rat strains. THC produced place avoidance, taste avoidance, and aversive taste reactivity responses in both strains. The Lewis strain displayed more aversive taste reactions and a stronger taste avoidance when conditioned with lower doses of THC than did the Sprague-Dawley strain of rats. THC is an anomalous drug of abuse that appears to be aversive to rats when assessed by these measures.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0735-7044
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7734082-Animals,
pubmed-meshheading:7734082-Avoidance Learning,
pubmed-meshheading:7734082-Conditioning, Classical,
pubmed-meshheading:7734082-Dose-Response Relationship, Drug,
pubmed-meshheading:7734082-Drinking,
pubmed-meshheading:7734082-Male,
pubmed-meshheading:7734082-Motivation,
pubmed-meshheading:7734082-Orientation,
pubmed-meshheading:7734082-Rats,
pubmed-meshheading:7734082-Rats, Inbred Lew,
pubmed-meshheading:7734082-Rats, Sprague-Dawley,
pubmed-meshheading:7734082-Species Specificity,
pubmed-meshheading:7734082-Taste,
pubmed-meshheading:7734082-Tetrahydrocannabinol
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pubmed:year |
1995
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pubmed:articleTitle |
THC-induced place and taste aversions in Lewis and Sprague-Dawley rats.
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pubmed:affiliation |
Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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