Linked Life Data

7733643

Source:http://linkedlifedata.com/resource/pubmed/id/7733643

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-6-1
pubmed:abstractText
Direct antitumor effect of cepharanthin (CEP) and the combined effect with adriamycin (ADR), as well as the effect of CEP against body weight loss caused by treatment of ADR were evaluated using ICR mice bearing Ehrlich ascites tumor. Single administration of CEP reduced tumor growth compared to that of the untreated control, but not significantly. However, multiple administration of CEP reduced the tumor growth significantly compared to that of the untreated control (p < 0.001). Simultaneous administration of intratumoral CEP and intravenous ADR reduced the tumor growth significantly compared to that of ADR alone (p < 0.05). Further, CEP restored body weight loss caused by the treatment of ADR (p < 0.01). These findings indicate that the combined administration of CEP and ADR may be effective in cancer treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-70
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Direct antitumor effect of cepharanthin and combined effect with adriamycin against Ehrlich ascites tumor in mice.
pubmed:affiliation
Department of Radiology, Okayama University Medical School, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't