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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1995-6-1
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pubmed:abstractText |
9 pregnancies (in 6 women) complicated by autoimmune thrombocytopenia were studied. Corticosteroids and/or azathioprine and/or intravenous immunoglobulins (IgG i.v.) were administered to 5 women during pregnancy. 1 complete remission (CR) was achieved after 3 mo. of treatment by corticosteroids and azathioprine. In peripartum period the treatment was administered in 7 cases (corticosteroids, IgG i.v., platelet transfusion). There were no haemorrhagic complications during peripartum period (8 vaginal delivery, 1 cesarean section). In 3 of 5 examined cases IgG antiplatelet antibody was detected. Study group was to small to define the correlation between level of antiplatelet antibodies and neonatal thrombocytopenia. 10 infants were born. 4 infants (including siblings) were found to have normal platelet counts immediately after delivery. They mothers were treated by IgG i.v. in 2 cases and 1 women in CR at the time of delivery. 4 infants were thrombocytopenic but required no treatment. Duration time of thrombocytopenia was 1 to 4 weeks. In these cases mothers were treated only by corticosteroids or had no therapy.
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pubmed:language |
pol
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0017-0011
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
553-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7729714-Adrenal Cortex Hormones,
pubmed-meshheading:7729714-Adult,
pubmed-meshheading:7729714-Autoimmune Diseases,
pubmed-meshheading:7729714-Azathioprine,
pubmed-meshheading:7729714-Female,
pubmed-meshheading:7729714-Humans,
pubmed-meshheading:7729714-Immunoglobulins, Intravenous,
pubmed-meshheading:7729714-Infant, Newborn,
pubmed-meshheading:7729714-Pregnancy,
pubmed-meshheading:7729714-Pregnancy Complications, Hematologic,
pubmed-meshheading:7729714-Pregnancy Outcome,
pubmed-meshheading:7729714-Remission Induction,
pubmed-meshheading:7729714-Thrombocytopenia,
pubmed-meshheading:7729714-Treatment Outcome
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pubmed:year |
1994
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pubmed:articleTitle |
[Autoimmune thrombocytopenia in pregnant women: diagnosis, treatment and prevention of complications in children].
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pubmed:affiliation |
Kliniki Hematologicznej Instytutu Hematologii i Transfuzjologii, Warszawa.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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