Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-6-1
pubmed:abstractText
Sedation of ventilated patients in the Intensive Care Unit generates a tension between adequate sedation to maintain comfort and ease of ventilation and over sedation with undesirable prolongation of ventilation and delays in discharge. Studies in animals suggest very low dose midazolam, but not higher doses, potentiate the sedative effects of opiates. We undertook a trial of opiate sedation versus opiate sedation plus low dose midazolam (1 mg/hour) to determine whether a similar effect could be demonstrated in man. Although ventilator time and the duration of admission to Intensive Care was not prolonged by the addition of midazolam, we were unable to demonstrate any statistically significant benefit with regard to memory recall.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
N
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1036-7314
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
22-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Failure of intravenous low dose midazolam to influence memory recall in drug paralysed post-operative patients sedated with papaveretum.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial