Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-5-30
pubmed:abstractText
Given the inhibition of gastric secretion by the "D" cells producing somatostatin in antral mucosa, as well as evidence of disorders of the postprandial blood glucose after antrectomy, we may expect as a result of the antral resection a series of modifications in the content of the "D" cells in duodenum and pancreas. The study group was made up of 30 Sprague-Dawley albino rats, distributed in 3 groups as follows: Billroth I, Billroth II and laparotomy. The "D" cell study and the morphometric analysis after immunohistochemical avidin-biotin, was carried out with an automatic image analyzer and a morphometric calculation program. The results show that: the "D" cell population decreased significantly in the B-II group while the number of pancreatic islets and the average insular surface, did not show significantly differences in the tree groups, the relationship of the average insular surface with respect to the pancreas, decreased significantly in the two groups with antrectomy, expressing a hyperplasia of the exocrine pancreas and that the number of insular "D" cells decreased significantly in the B-II group and didn't change in the B-I group. These findings suggest that antrectomy, originates an increase of the exocrine pancreas and that antrectomy with gastrojejunal anastomosis excluding the duodenum, decreases the number of duodenal "D" cells and number of "D" cells of the pancreatic islets.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1130-0108
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Morphometric study of somatostatin-producing "D" cells in duodenum and pancreas of the rat, following experimental antrectomy].
pubmed:affiliation
Servicio de Cirugía General, Hospital de Mollet, Universidad Autónoma Barcelona.
pubmed:publicationType
Journal Article, English Abstract