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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-5-25
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pubmed:abstractText |
The cross-reactivity of l-methamphetamine (l-desoxyephedrine) to the EMIT-d.a.u. class (EC) and EMIT-d.a.u. monoclonal amphetamine/methamphetamine (EM) assays was evaluated in urine specimens collected from six subjects using Vicks inhalers. The subjects were five men and a woman ranging from 27 to 47 years old. Four subjects used the inhaler as recommended by the manufacturer for five consecutive days; two subjects used double this dosage for three consecutive days. All urine voids were collected, totaling 132 specimens. All specimens were analyzed by the EC and EM assays. Specimens yielding a positive response were then analyzed by chiral and achiral gas chromatography/mass spectrometry (GC/MS). No specimen was positive by the EM assay, whereas 17 specimens yielded positive EC results. One subject for form the "as recommended" group had six positive specimens with maximum l-desoxyephedrine of 872 ng/ml. Both subjects using twice the recommended dosage had positive specimens, maximum l-desoxyephedrine of 1,560 ng/ml. No positive specimen contained > 200 ng/ml l-amphetamine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0163-4356
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7725384-Administration, Inhalation,
pubmed-meshheading:7725384-Adult,
pubmed-meshheading:7725384-Amphetamine,
pubmed-meshheading:7725384-Antibodies, Monoclonal,
pubmed-meshheading:7725384-Cross Reactions,
pubmed-meshheading:7725384-Enzyme Multiplied Immunoassay Technique,
pubmed-meshheading:7725384-False Positive Reactions,
pubmed-meshheading:7725384-Female,
pubmed-meshheading:7725384-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:7725384-Humans,
pubmed-meshheading:7725384-Male,
pubmed-meshheading:7725384-Methamphetamine,
pubmed-meshheading:7725384-Middle Aged
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pubmed:year |
1995
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pubmed:articleTitle |
Response of EMIT amphetamine immunoassays to urinary desoxyephedrine following Vicks inhaler use.
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pubmed:affiliation |
Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
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