rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1995-5-19
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pubmed:abstractText |
Multicopy plasmids bearing a small internal portion of the RhsA genetic element of Escherichia coli K-12 imparted a viability block on cultures grown to stationary phase in broth. Inclusion of the last 25 codons of the RhsA core open reading frame (called core-ORF) in the plasmid insert was crucial for eliciting this toxic effect. The toxic effect could be suppressed by including the adjacent Rhs component, dsORF-a1, on the multicopy plasmid. The toxic effect was enhanced in RpoS- strains.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-1307487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-1429465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-1648559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-1729229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-1849609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-2165476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-2403547,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-2478072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-2644231,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-3312987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6086936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6087326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6235151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6263926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6271456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6323249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-6988668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-7934896,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-8257118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-8276245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-8316082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-8387990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7721712-8425216
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-9193
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2209-13
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7721712-Bacterial Proteins,
pubmed-meshheading:7721712-Base Sequence,
pubmed-meshheading:7721712-Chromosome Mapping,
pubmed-meshheading:7721712-Cloning, Molecular,
pubmed-meshheading:7721712-DNA, Bacterial,
pubmed-meshheading:7721712-Escherichia coli,
pubmed-meshheading:7721712-Genes, Bacterial,
pubmed-meshheading:7721712-Interphase,
pubmed-meshheading:7721712-Molecular Sequence Data,
pubmed-meshheading:7721712-Open Reading Frames,
pubmed-meshheading:7721712-Plasmids,
pubmed-meshheading:7721712-Sigma Factor,
pubmed-meshheading:7721712-Suppression, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
A stationary-phase-dependent viability block governed by two different polypeptides from the RhsA genetic element of Escherichia coli K-12.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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