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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-5-22
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pubmed:abstractText |
Here we report on a case of chronic granulomatous disease (CGD) in a 3-year-old boy who suffered from severe repeated bacterial infections including multiple liver abscesses. The case is of interest because (1) the disease is very rare (it is the first case of CGD diagnosed at the Clinic for Pediatric Medicine, University of Innsbruck), (2) the diagnosis, based on clinical parameters and the nitrobluetetrazolium test was completed and validated by single-cell measurements of respiratory-burst activity of the patient's granulocytes in a fluorescence-activated cell sorter (FACS), and (3) the applied FACS method, adapted in our laboratory, presents one of the most sensitive and reliable methods to evaluate this aspect of disturbed granulocyte function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
425-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7719159-Cell Separation,
pubmed-meshheading:7719159-Child, Preschool,
pubmed-meshheading:7719159-Flow Cytometry,
pubmed-meshheading:7719159-Granulocytes,
pubmed-meshheading:7719159-Granulomatous Disease, Chronic,
pubmed-meshheading:7719159-Humans,
pubmed-meshheading:7719159-Male,
pubmed-meshheading:7719159-Neutrophils,
pubmed-meshheading:7719159-Respiratory Burst
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pubmed:year |
1995
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pubmed:articleTitle |
Chronic granulomatous disease assessed by single-cell granulocyte oxidative burst activity.
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pubmed:affiliation |
Institute for General and Experimental Pathology, School of Medicine, University of Innsbruck, Austria.
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pubmed:publicationType |
Journal Article,
Case Reports
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