Linked Life Data

7717485

Source:http://linkedlifedata.com/resource/pubmed/id/7717485

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-5-18
pubmed:abstractText
The accidental intravascular injection of bupivacaine or etidocaine epidurally has resulted in several maternal deaths. To be effective, a test dose must allow detection of intravenous catheter placement and prevent accidental intravenous injection. This study was designed to determine the dose of lignocaine required for this purpose. Sixty healthy gynaecological patients were allocated randomly to receive an intravenous dose of normal saline (group 1), lignocaine 0.5 mg.kg-1 (group 2) or 1 mg.kg-1 (group 3) 3 min prior to induction of anaesthesia. At 1 min intervals the patients were asked about subjective symptoms produced by this 'test dose'. In group 2 only 50% of patients reported a positive test dose, whereas in the patients of group 3, a significantly greater percentage (95%) had a positive test dose (p < 0.01). This suggests that the use of 1 mg.kg-1 lignocaine as a test dose would result in a significantly higher sensitivity for detecting intravascular injection than the use of 0.5 mg.kg-1.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0003-2409
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Lignocaine test dose to detect intravenous injection.
pubmed:affiliation
Anaesthetic Department, St James's University Hospital, Leeds, West Yorkshire.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial