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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-5-17
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pubmed:abstractText |
In the present study, susceptibility to Pentylentetrazol (PTZ)-induced seizures was tested in 45 four-wk old rats born to mothers exposed to moderate asphyxia in the last week of pregnancy by breathing N2 99.9% for 6 min in two separate sessions, (Group I--experimental rats) and in 44 rats of the same age, born after a normal pregnancy (Group II--controls). The results showed that the experimental rats, following episodes of asphyxia in intrauterine life, had a higher susceptibility to PTZ-induced seizures than the controls, manifested by earlier onset of convulsions and a higher incidence of fetal epileptic status. This occurred despite normal development and the absence of neurological deficits in the experimental rats in the first 4 wk of extrauterine life.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0031-9384
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
315-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:7716209-Animals,
pubmed-meshheading:7716209-Electrocardiography,
pubmed-meshheading:7716209-Female,
pubmed-meshheading:7716209-Fetal Hypoxia,
pubmed-meshheading:7716209-Male,
pubmed-meshheading:7716209-Pentylenetetrazole,
pubmed-meshheading:7716209-Pregnancy,
pubmed-meshheading:7716209-Prenatal Exposure Delayed Effects,
pubmed-meshheading:7716209-Rats,
pubmed-meshheading:7716209-Rats, Wistar,
pubmed-meshheading:7716209-Seizures
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pubmed:year |
1995
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pubmed:articleTitle |
Effect of fetal hypoxia on seizure susceptibility in rats.
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pubmed:affiliation |
Department of Traumatology, Orthopedy and Occupational Medicine, University of Turin, Italy.
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pubmed:publicationType |
Journal Article
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