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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-5-18
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pubmed:abstractText |
A large outbreak of acute gastroenteritis occurred over a 5-week period aboard an aircraft carrier. The estimated cumulative attack rate was 13% among the 4,500-man crew. Eight percent of the crew sought medical attention, nearly all of whom missed 1 day or more of work. The risk of developing illness was 2 to 3 times greater for individuals living in more crowded sleeping quarters (> 50 persons per compartment). Occurrence of gastroenteritis was associated with a fourfold or more rise in Norwalk virus antibody levels, as measured by an enzyme-linked immunoassay utilizing a baculovirus expressed recombinant antigen. In addition, 27 nm Norwalk virus-like particles were visualized in two of six stools examined by immune electron microscopy. The presence of a low (< 1:50) or a high (> or = 1:6,400) pre-illness antibody level was associated with a lower incidence of illness. This investigation indicates that Norwalk virus can adversely impact operations of a military vessel and that crowding is a major risk factor in transmission.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-6615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
61-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7714493-Acute Disease,
pubmed-meshheading:7714493-Adolescent,
pubmed-meshheading:7714493-Adult,
pubmed-meshheading:7714493-Antibodies, Viral,
pubmed-meshheading:7714493-Caliciviridae Infections,
pubmed-meshheading:7714493-Disease Outbreaks,
pubmed-meshheading:7714493-Gastroenteritis,
pubmed-meshheading:7714493-Humans,
pubmed-meshheading:7714493-Incidence,
pubmed-meshheading:7714493-Male,
pubmed-meshheading:7714493-Middle Aged,
pubmed-meshheading:7714493-Military Personnel,
pubmed-meshheading:7714493-Naval Medicine,
pubmed-meshheading:7714493-Norwalk virus,
pubmed-meshheading:7714493-Risk Factors,
pubmed-meshheading:7714493-Ships,
pubmed-meshheading:7714493-United States
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pubmed:year |
1995
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pubmed:articleTitle |
Epidemiology of Norwalk virus during an outbreak of acute gastroenteritis aboard a US aircraft carrier.
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pubmed:affiliation |
U.S. Navy Environmental and Preventive Medicine Unit No. 7, Naples, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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