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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1995-5-17
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pubmed:abstractText |
An acute myopathy complicating life-threatening asthma has been reported with increasing frequency. We present a further 3 patients with this complication. Each patient had nerve conduction studies, electromyography and muscle biopsy performed. The records of a cohort of 12 patients, ventilated in an intensive care unit over a 16 month period, were reviewed. Eleven out of the 12 patients developed an elevated creatine kinase level (median 1311 U/L, range 185-9973 U/L) and 4 developed symptomatic weakness. The myopathy of status asthmaticus is not a homogeneous clinicopathological entity. Although myopathy is the predominant feature, there is a neuropathic component in some patients. Full recovery is usual. The combination of corticosteroids and neuromuscular blocking agents has been proposed as the possible cause of the complication.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0196-6383
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
72-81
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7712631-Acute Disease,
pubmed-meshheading:7712631-Adult,
pubmed-meshheading:7712631-Aged,
pubmed-meshheading:7712631-Albuterol,
pubmed-meshheading:7712631-Biopsy,
pubmed-meshheading:7712631-Cohort Studies,
pubmed-meshheading:7712631-Drug Therapy, Combination,
pubmed-meshheading:7712631-Electromyography,
pubmed-meshheading:7712631-Female,
pubmed-meshheading:7712631-Humans,
pubmed-meshheading:7712631-Hydrocortisone,
pubmed-meshheading:7712631-Muscles,
pubmed-meshheading:7712631-Muscular Diseases,
pubmed-meshheading:7712631-Neural Conduction,
pubmed-meshheading:7712631-Neuromuscular Blocking Agents,
pubmed-meshheading:7712631-Status Asthmaticus
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pubmed:year |
1993
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pubmed:articleTitle |
Acute myopathy in status asthmaticus.
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pubmed:affiliation |
Neurology Unit, John Hunter Hospital, Newcastle, New South Wales.
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pubmed:publicationType |
Journal Article,
Case Reports
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