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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1995-5-15
|
| pubmed:abstractText |
Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain the NFD. Dephosphorylation markedly reduces the positivity of AT8. Using PLP-fixed tissue, monoclonal antibody Tau-1 also immunostains aluminum-induced NFD.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0006-8993
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
16
|
| pubmed:volume |
669
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-9
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7712190-Aluminum,
pubmed-meshheading:7712190-Animals,
pubmed-meshheading:7712190-Antibodies,
pubmed-meshheading:7712190-Brain,
pubmed-meshheading:7712190-Immunohistochemistry,
pubmed-meshheading:7712190-Medulla Oblongata,
pubmed-meshheading:7712190-Mesencephalon,
pubmed-meshheading:7712190-Nerve Degeneration,
pubmed-meshheading:7712190-Neurofibrillary Tangles,
pubmed-meshheading:7712190-Rabbits,
pubmed-meshheading:7712190-tau Proteins
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Tau immunoreactivity associated with aluminum maltolate-induced neurofibrillary degeneration in rabbits.
|
| pubmed:affiliation |
Department of Pathology, University of Virginia Health Sciences Center, Charlottesville 22908.
|
| pubmed:publicationType |
Journal Article
|