Linked Life Data

7711492

Source:http://linkedlifedata.com/resource/pubmed/id/7711492

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-5-16
pubmed:abstractText
Positive neuropsychiatric features (paranoia, delusions, hallucinations) and negative features (disinterest/withdrawal, apathy, reduced speech output, reduced physical activity) occur in Alzheimer's disease (AD), although most studies have focused on positive features alone. Positive features may be associated with a more severe and rapidly progressive subtype of AD. A retrospective analysis of prospectively obtained research data (101 probable AD patients) revealed that patients with positive features had been ill longer but were otherwise similar to patients with negative features. Patients with any neuropsychiatric features had more rapid progression and more severe cognitive and comprehension deficits than patients without such features. Neuropsychiatric features in AD likely reflect variations in mesocortical and mesolimbic degeneration rather than an etiologic or prognostic subtype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0895-0172
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
54-60
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Positive and negative neuropsychiatric features in Alzheimer's disease.
pubmed:affiliation
Baylor College of Medicine, Alzheimer's Disease Research Center, Houston, Texas 77030, USA.
pubmed:publicationType
Journal Article