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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1995-5-15
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pubmed:databankReference |
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pubmed:abstractText |
The thyroid transcription factor 1 (TTF-1) is a homeodomain-containing transcription factor that activates the transcriptional activity of thyroid-specific gene promoters by binding to them. Hence, TTF-1 is crucial in the maintenance of the thyroid differentiation phenotype. The authors isolated and analysed the human TTF-1 gene, which shows a striking homology with the rat TTF-1 gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-3002
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
1261
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7711080-Base Sequence,
pubmed-meshheading:7711080-Cell Differentiation,
pubmed-meshheading:7711080-Cloning, Molecular,
pubmed-meshheading:7711080-Gene Expression Regulation,
pubmed-meshheading:7711080-Humans,
pubmed-meshheading:7711080-Iodide Peroxidase,
pubmed-meshheading:7711080-Molecular Sequence Data,
pubmed-meshheading:7711080-Nuclear Proteins,
pubmed-meshheading:7711080-Receptors, Thyrotropin,
pubmed-meshheading:7711080-Sequence Homology, Nucleic Acid,
pubmed-meshheading:7711080-Thyroglobulin,
pubmed-meshheading:7711080-Transcription Factors
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pubmed:year |
1995
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pubmed:articleTitle |
Cloning and sequence analysis of human thyroid transcription factor 1.
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pubmed:affiliation |
Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, Laboratory of Cellular and Molecular Endocrinology, Santa Maria Imbaro, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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