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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1995-5-8
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pubmed:abstractText |
The neuropathological changes of Alzheimer's disease occur universally in individuals with Down's syndrome as they reach middle age and worsen with increasing age. Thus, evaluation of patients of various ages with Down's syndrome allows one to construct a life history of the development of neuropathological changes associated with Alzheimer's disease at various points in the disease process.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-9942
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7710373-Adolescent,
pubmed-meshheading:7710373-Adult,
pubmed-meshheading:7710373-Aging,
pubmed-meshheading:7710373-Alzheimer Disease,
pubmed-meshheading:7710373-Apolipoprotein E4,
pubmed-meshheading:7710373-Apolipoproteins E,
pubmed-meshheading:7710373-Child,
pubmed-meshheading:7710373-Child, Preschool,
pubmed-meshheading:7710373-Dementia,
pubmed-meshheading:7710373-Down Syndrome,
pubmed-meshheading:7710373-Female,
pubmed-meshheading:7710373-Genotype,
pubmed-meshheading:7710373-Hippocampus,
pubmed-meshheading:7710373-Humans,
pubmed-meshheading:7710373-Male,
pubmed-meshheading:7710373-Middle Aged,
pubmed-meshheading:7710373-Neurofibrillary Tangles
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pubmed:year |
1995
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pubmed:articleTitle |
Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype.
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pubmed:affiliation |
Neurology Service, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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