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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1995-5-11
|
| pubmed:abstractText |
Intimal hyperplasia (IH) is a proliferative process of vascular smooth muscle cells that occurs after an arterial injury, particularly at outflow anastomoses of prosthetic bypass grafts. IH causes stenosis that leads ultimately to graft flow reduction and thrombosis. We have demonstrated previously that vein cuff interposition between an expanded polytetrafluoroethylene (e-PTFE) graft and artery at distal anastomoses diminished IH formation in the arterial outflow as compared with noncuffed anastomoses. Improved long-term patency rates associated with the placement of an interposition vein cuff at the distal anastomosis of e-PTFE grafts to infrageniculate arteries have also been demonstrated clinically. This study examined the mechanical factors that may contribute to the protective effect of cuffed anastomoses. These factors include the expansibility of the vein cuff as compared with e-PTFE, as well as the angle of the cuffed anastomosis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0741-5214
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
21
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
558-64; discussion 564-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7707561-Anastomosis, Surgical,
pubmed-meshheading:7707561-Animals,
pubmed-meshheading:7707561-Blood Vessel Prosthesis,
pubmed-meshheading:7707561-Carotid Artery, Common,
pubmed-meshheading:7707561-Dogs,
pubmed-meshheading:7707561-Elasticity,
pubmed-meshheading:7707561-Graft Occlusion, Vascular,
pubmed-meshheading:7707561-Hyperplasia,
pubmed-meshheading:7707561-Muscle, Smooth, Vascular,
pubmed-meshheading:7707561-Platelet Aggregation,
pubmed-meshheading:7707561-Polytetrafluoroethylene,
pubmed-meshheading:7707561-Prosthesis Design,
pubmed-meshheading:7707561-Pulsatile Flow,
pubmed-meshheading:7707561-Stress, Mechanical,
pubmed-meshheading:7707561-Surface Properties,
pubmed-meshheading:7707561-Thrombosis,
pubmed-meshheading:7707561-Tunica Intima,
pubmed-meshheading:7707561-Vascular Patency,
pubmed-meshheading:7707561-Veins
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
The protective effect of vein cuffed anastomoses is not mechanical in origin.
|
| pubmed:affiliation |
Department of Surgery, George Washington University, Washington, DC, USA.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|