Linked Life Data

7705901

Source:http://linkedlifedata.com/resource/pubmed/id/7705901

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-5-11
pubmed:abstractText
In many biomedical research contexts, treatment effects are estimated from studies based on subjects who have been recruited because of high (low) measurements of a response variable, e.g., high blood pressure or low scores on a stress test. In this situation, simple change scores will overestimate the treatment effect; and the use of the paired t-test may find significant change due not to the treatment per se but, rather, due to regression towards the mean. A PC program implementing a procedure for adjusting the observed change for the regression effect in simple pre-test-post-test experiments is described, illustrated, and made available to interested readers. The method is due to Mee and Chua (Am Stat, 45 (1991) 39-42) and may be considered as an alternative to the paired t-test which separates the effect of the treatment from the so-called regression effect.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0020-7101
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-94
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
PC program implementing an alternative to the paired t-test which adjusts for regression to the mean.
pubmed:affiliation
Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor 48109.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.