Linked Life Data

7705737

Source:http://linkedlifedata.com/resource/pubmed/id/7705737

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-5-9
pubmed:abstractText
We report the allele and genotype frequencies in a sample of an unrelated native Kuwaiti population determined by the use of polymerase chain reaction (PCR) and reverse dot-blot analysis. This technique, involving the use of commercially available AmpliType HLA-DQ alpha forensic DNA amplification and typing kit, has permitted the definition of six alleles and 21 genotypes in a sample of 220 people. The allelic frequencies are in the range 5.7-27.5%. This locus demonstrated a heterozygosity of 0.80 with an allelic diversity of 0.81 and the power of discrimination (PD) was 0.93. The distribution of observed genotypes conformed to Hardy-Weinberg equilibrium thus indicating genetic equilibrium of the different variants. This population data should permit the use of HLA-DQ alpha marker for individual identification in forensic casework.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0379-0738
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
72
pubmed:geneSymbol
DDQA 4.3, DQA 1.1, DQA 1.2, DQA 1.3, DQA 2, DQA 3, DQA 4.1, DQA1, DQA1* 0101, DQA1* 0102, DQA1* 0103, DQA1* 0201, DQA1* 0301, DQA1* 0401, DQA1* 0501, DQA1* 0601, DQA2, DQA3, DQA4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
HLA-DQ alpha allele and genotype frequencies in a native Kuwaiti population.
pubmed:affiliation
Department of Biochemistry, Faculty of Medicine, Kuwait University.
pubmed:publicationType
Journal Article