Linked Life Data

7700006

Source:http://linkedlifedata.com/resource/pubmed/id/7700006

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-5-3
pubmed:abstractText
The production of angiotensinogen is controlled mainly by hormones that affect the concentration of its mRNA in tissues. Accordingly, hormones that act upon gene transcription play a prominent role. However, other factors may modulate the transcriptional effects of hormones, and these should be considered to appreciate the final effects of hormones on the secretion of angiotensinogen. The most important role played by hormones in the regulation of angiotensinogen may be to maintain its production in the face of rapid consumption by high levels of renin. However, elevated levels of angiotensinogen may become a risk factor in situations where the normal feedback regulation of renin does not operate normally. Finally, the synthesis of angiotensinogen in tissues may be regulated differentially than that in liver, although the exact importance of these observations is still poorly understood.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0085-2538
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1561-3
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Angiotensinogen: hormonal regulation and relative importance in the generation of angiotensin II.
pubmed:affiliation
Clinical Research Institute of Montreal, Québec, Canada.
pubmed:publicationType
Journal Article, Review