Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1995-5-2
|
pubmed:abstractText |
Antitumoral interleukin-2 (IL-2) therapy is frequently associated with a neurotoxicity that manifests itself in neuropsychiatric disturbances and, more rarely, with neurological focal signs. With the aim of documenting the involvement of cognitive functions after IL-2 treatment, we studied 20 patients using evoked cognitive potentials (P300) and computer analysis of the EEG signal. A comparison of the tests performed before and after the subcutaneous infusion of IL-2 showed a significant lengthening in mean P300 latencies and a percentage increase in the EEG frequencies contained with the delta and theta bands, especially in the frontal regions.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0392-0461
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
341-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:7698891-Adult,
pubmed-meshheading:7698891-Aged,
pubmed-meshheading:7698891-Brain,
pubmed-meshheading:7698891-Brain Mapping,
pubmed-meshheading:7698891-Electroencephalography,
pubmed-meshheading:7698891-Evoked Potentials, Visual,
pubmed-meshheading:7698891-Female,
pubmed-meshheading:7698891-Humans,
pubmed-meshheading:7698891-Interleukin-2,
pubmed-meshheading:7698891-Male,
pubmed-meshheading:7698891-Middle Aged,
pubmed-meshheading:7698891-Neoplasms,
pubmed-meshheading:7698891-Nervous System Diseases
|
pubmed:year |
1994
|
pubmed:articleTitle |
Neurotoxicity of antitumoral IL-2 therapy: evoked cognitive potentials and brain mapping.
|
pubmed:affiliation |
Servizio di Neurologia, Istituto Regina Elena per lo Studio e la Cura di Tumori, Roma.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|