Linked Life Data

7694561

Source:http://linkedlifedata.com/resource/pubmed/id/7694561

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-12-17
pubmed:abstractText
Three synthetic peptides corresponding to amino acid sequences of two human chorionic gonadotropin (hCG) subunits were conjugated to thyroglobulin and used for immunization of rabbits. The highest antibody concentration was found in antisera from rabbits immunized with the peptide corresponding to 122-145 sequence of the hormone beta-subunit. Specificity of antisera and immunoaffinity purified rabbit antibodies were studied. Antibody anti-122-145-beta hCG with antibody anti-beta hCG conjugated to peroxidase were suitable for sensitive and specific enzyme immunoassay of hCG and beta hCG. Good correlation was noted between assay of the hormone in sera of patients with trophoblastic diseases or in urine of pregnant women by ELISA with the rabbit antibody pair and by commercial kit or by ELISA with two monoclonal antibodies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-069X
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Rabbit antibodies to some sequences of human chorionic gonadotropin and their use for immunoassay of the hormone.
pubmed:affiliation
Biochemical Laboratory, Institute of Immunology and Experimental Therapy, Wroc?aw, Poland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't