| pubmed-article:7691687 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C1327616 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0041236 | lld:lifeskim |
| pubmed-article:7691687 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:7691687 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7691687 | pubmed:dateCreated | 1993-11-4 | lld:pubmed |
| pubmed-article:7691687 | pubmed:abstractText | Pancreatic secretory trypsin inhibitor (PSTI) has been suggested to be an acute-phase reactant in humans and to be induced by inflammatory cytokines such as the interleukins IL-1 and IL-6. We report that PSTI is synthesized in hepatoma cells and that the gene expression is augmented by IL-6. The start points (tsp) for basal and augmented transcription are exactly the same as the tsp in normal pancreas. Analysis of the PSTI gene revealed that a 40-bp DNA fragment located between kb -3.84 and -3.80 carries the element responsible for both transcriptional activity and IL-6-induced gene expression. This 40-bp fragment contains TTGNNGNAATG, the consensus sequence for the NF-IL6-binding site, which is also known as the IL-6-responsive element that is conserved among various acute-phase genes. The basal activity was augmented by another sequence that lies between kb -4.0 and -3.9. | lld:pubmed |
| pubmed-article:7691687 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7691687 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7691687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691687 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7691687 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7691687 | pubmed:issn | 0378-1119 | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:MoriTT | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:YasudaTT | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:OgawaMM | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:MatsubaraKK | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:MurataAA | lld:pubmed |
| pubmed-article:7691687 | pubmed:author | pubmed-author:OhmachiYY | lld:pubmed |
| pubmed-article:7691687 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7691687 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:7691687 | pubmed:volume | 131 | lld:pubmed |
| pubmed-article:7691687 | pubmed:geneSymbol | IL6-RE | lld:pubmed |
| pubmed-article:7691687 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7691687 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7691687 | pubmed:pagination | 275-80 | lld:pubmed |
| pubmed-article:7691687 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:meshHeading | pubmed-meshheading:7691687-... | lld:pubmed |
| pubmed-article:7691687 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7691687 | pubmed:articleTitle | Identification of the IL-6-responsive element in an acute-phase-responsive human pancreatic secretory trypsin inhibitor-encoding gene. | lld:pubmed |
| pubmed-article:7691687 | pubmed:affiliation | Department of Surgery II, Osaka University Medical School, Japan. | lld:pubmed |
| pubmed-article:7691687 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7691687 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7691687 | lld:pubmed |
