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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-11-1
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pubmed:abstractText |
We report the use of serum prostate specific antigen (PSA) estimations prior to clinic attendance in 234 patients referred with symptoms of bladder outlet obstruction to a general urology clinic. Ninety-three patients with PSA levels > 10 ng/ml were seen earlier than planned and offered transurethral resection or transrectal biopsy of the prostate gland. Forty-six patients (49%) proved to have carcinoma of the prostate, compared with 10 of 141 (7%) patients who had PSA values < 10 ng/ml. With a decision value of 10 ng/ml, the sensitivity for detecting carcinoma was 82% and specificity 73.5%. Using a decision value of 7 ng/ml improved the sensitivity to 95% without significantly affecting the specificity (70%). Twenty-four patients with prostatic cancer had bone metastases; the sensitivity of PSA for predicting a positive bone scan using a decision value of 25 ng/ml was 92%, but the specificity was only 31%.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-1331
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7691370-Adult,
pubmed-meshheading:7691370-Aged,
pubmed-meshheading:7691370-Aged, 80 and over,
pubmed-meshheading:7691370-Bone Neoplasms,
pubmed-meshheading:7691370-Humans,
pubmed-meshheading:7691370-Male,
pubmed-meshheading:7691370-Middle Aged,
pubmed-meshheading:7691370-Prospective Studies,
pubmed-meshheading:7691370-Prostate-Specific Antigen,
pubmed-meshheading:7691370-Prostatic Neoplasms,
pubmed-meshheading:7691370-Sensitivity and Specificity,
pubmed-meshheading:7691370-Urethral Obstruction
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pubmed:year |
1993
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pubmed:articleTitle |
Routine estimation of prostate specific antigen prior to clinic attendance in patients with symptoms of bladder outlet obstruction.
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pubmed:affiliation |
Department of Urology, Broadgreen Hospital, Liverpool.
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pubmed:publicationType |
Journal Article
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