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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-11-4
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pubmed:abstractText |
Lymphocyte subset abnormalities have been observed in a series of patients diagnosed with Wegener's granulomatosis (WG). Fifteen patients with WG were evaluated for lymphocyte subset abnormalities by two-color immunofluorescence flow cytometry. The WG group showed a decrease in CD4+ cells and an extraordinary increase in HLA-DR+ cells. The average percentages of HLA-DR+ cells of the normal group and WG group were 11.0 +/- 4.0 and 40.5 +/- 13.9% (CD3+HLA-DR+ = 20.3 + 9.4%). Within the CD8 family, CD8+57+, CD8+38+ and CD8+HLA-DR+ cells were markedly elevated. Our findings differ from other series which reported that the lymphocyte subsets in the peripheral blood of patients with WG were normal.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7691301-Adult,
pubmed-meshheading:7691301-Antigens, CD,
pubmed-meshheading:7691301-Antigens, CD57,
pubmed-meshheading:7691301-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:7691301-CD4-Positive T-Lymphocytes,
pubmed-meshheading:7691301-Female,
pubmed-meshheading:7691301-Flow Cytometry,
pubmed-meshheading:7691301-HLA-DR Antigens,
pubmed-meshheading:7691301-Humans,
pubmed-meshheading:7691301-Immunophenotyping,
pubmed-meshheading:7691301-Leukocyte Count,
pubmed-meshheading:7691301-Lymphocyte Subsets,
pubmed-meshheading:7691301-Male,
pubmed-meshheading:7691301-Middle Aged,
pubmed-meshheading:7691301-T-Lymphocytes, Regulatory,
pubmed-meshheading:7691301-Wegener Granulomatosis
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pubmed:year |
1993
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pubmed:articleTitle |
Distinctive increases in HLA-DR+ and CD8+57+ lymphocyte subsets in Wegener's granulomatosis.
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pubmed:affiliation |
Department of Otolaryngology, National Defense Medical College, Saitama, Japan.
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pubmed:publicationType |
Journal Article
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