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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1993-9-15
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pubmed:abstractText |
Recently, significant progress had been made in understanding the T-B lymphocyte interactions that control humoral immunity. This review highlights experiments that demonstrate a central role for interactions between T-cell-B-cell-activating molecule (CD40 ligand) expressed on T cells and CD40 on B cells in B-cell activation and immunoglobulin isotype switching, both in vitro and in vivo.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0952-7915
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
439-44
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7688518-Animals,
pubmed-meshheading:7688518-Antibody Formation,
pubmed-meshheading:7688518-Antigens, CD,
pubmed-meshheading:7688518-Antigens, CD40,
pubmed-meshheading:7688518-Antigens, Differentiation, B-Lymphocyte,
pubmed-meshheading:7688518-B-Lymphocyte Subsets,
pubmed-meshheading:7688518-CD40 Ligand,
pubmed-meshheading:7688518-Cell Adhesion,
pubmed-meshheading:7688518-Cell Differentiation,
pubmed-meshheading:7688518-Cricetinae,
pubmed-meshheading:7688518-Humans,
pubmed-meshheading:7688518-Lymphocyte Activation,
pubmed-meshheading:7688518-Lymphocyte Cooperation,
pubmed-meshheading:7688518-Lymphokines,
pubmed-meshheading:7688518-Membrane Glycoproteins,
pubmed-meshheading:7688518-Mice,
pubmed-meshheading:7688518-Models, Biological,
pubmed-meshheading:7688518-Signal Transduction,
pubmed-meshheading:7688518-T-Lymphocytes, Helper-Inducer
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pubmed:year |
1993
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pubmed:articleTitle |
Non-antigen signals for B-cell growth and differentiation to antibody secretion.
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pubmed:affiliation |
Columbia University, College of Physicians and Surgeons, New York.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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