| pubmed-article:7687750 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7687750 | lifeskim:mentions | umls-concept:C0035668 | lld:lifeskim |
| pubmed-article:7687750 | lifeskim:mentions | umls-concept:C0001480 | lld:lifeskim |
| pubmed-article:7687750 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:7687750 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:7687750 | pubmed:issue | 6437 | lld:pubmed |
| pubmed-article:7687750 | pubmed:dateCreated | 1993-8-26 | lld:pubmed |
| pubmed-article:7687750 | pubmed:abstractText | RNAs that contain specific high-affinity binding sites for small molecule ligands immobilized on a solid support are present at a frequency of roughly one in 10(10)-10(11) in pools of random sequence RNA molecules. Here we describe a new in vitro selection procedure designed to ensure the isolation of RNAs that bind the ligand of interest in solution as well as on a solid support. We have used this method to isolate a remarkably small RNA motif that binds ATP, a substrate in numerous biological reactions and the universal biological high-energy intermediate. The selected ATP-binding RNAs contain a consensus sequence, embedded in a common secondary structure. The binding properties of ATP analogues and modified RNAs show that the binding interaction is characterized by a large number of close contacts between the ATP and RNA, and by a change in the conformation of the RNA. | lld:pubmed |
| pubmed-article:7687750 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7687750 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7687750 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7687750 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7687750 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:7687750 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:7687750 | pubmed:author | pubmed-author:SzostakJ WJW | lld:pubmed |
| pubmed-article:7687750 | pubmed:author | pubmed-author:SassanfarMM | lld:pubmed |
| pubmed-article:7687750 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7687750 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:7687750 | pubmed:volume | 364 | lld:pubmed |
| pubmed-article:7687750 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7687750 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7687750 | pubmed:pagination | 550-3 | lld:pubmed |
| pubmed-article:7687750 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:meshHeading | pubmed-meshheading:7687750-... | lld:pubmed |
| pubmed-article:7687750 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7687750 | pubmed:articleTitle | An RNA motif that binds ATP. | lld:pubmed |
| pubmed-article:7687750 | pubmed:affiliation | Department of Genetics, Harvard Medical School, Boston, Massachusetts. | lld:pubmed |
| pubmed-article:7687750 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7687750 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7687750 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7687750 | lld:pubmed |
