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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-7-27
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pubmed:abstractText |
A 51-year-old female was who admitted complaining of cough and slight fever and lower limb petechia. The laboratory examinations revealed leukocytosis (49,400/microliters) with blasts (71%) in the peripheral blood. The NCC was 30 x 10(4)/microliters with 84.8% blasts in the bone marrow. Myeloperoxidase staining was positive for 6% of blasts. Auer rods were not seen in some blasts. Thus, acute myeloblastic leukemia (M1) was diagnosed according to FAB classification. In the peripheral blood, 43.3% of blasts expressed CD19, 10.3% of blasts expressed CD20 and 55.6% of blasts expressed CD33 on admission. Though she received two courses of DCMP according to the DCMP-85 protocol, and one combined course of mitoxantrone, etoposide, and Ara-C. The NCC was 20.0 x 10(4)/microliters with 70% blasts in the bone marrow. CD19 was expressed by 72.4% of blasts and 35.0% expressed CD20. The ALL-90 protocol was started, but remission was not achieved. Thus this case was considered to be acute mixed lineage leukemia.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD19,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/CD33 antigen
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0485-1439
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
643-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7686236-Antigens, CD,
pubmed-meshheading:7686236-Antigens, CD19,
pubmed-meshheading:7686236-Antigens, Differentiation, B-Lymphocyte,
pubmed-meshheading:7686236-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:7686236-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7686236-B-Lymphocytes,
pubmed-meshheading:7686236-Drug Resistance,
pubmed-meshheading:7686236-Female,
pubmed-meshheading:7686236-Humans,
pubmed-meshheading:7686236-Leukemia, Myeloid, Acute,
pubmed-meshheading:7686236-Middle Aged,
pubmed-meshheading:7686236-Precursor Cell Lymphoblastic Leukemia-Lymphoma
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pubmed:year |
1993
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pubmed:articleTitle |
[Acute mixed lineage leukemia showing resistance to AML and ALL therapy].
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pubmed:affiliation |
Third Department of Internal Medicine, Nihon University School of Medicine.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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