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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
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pubmed:dateCreated |
1993-6-3
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pubmed:abstractText |
Effect of Chlordecone (Cd) and malnutrition on total body and spleen weights, and plaque forming cells (PFC) were studied. Rats were fed on normal, calcium (Ca-D), protein (P-D) or Ca+P-deficient diets containing 0, 10 or 100 ppm of Cd for 2 or 4 weeks. High (95-100%) mortality was observed in malnourished rats treated with 100 ppm of Cd for 4 weeks. A slight decrease in body weight and an increase in spleen weight was observed in normal but not malnourished rats treated with 10 ppm of Cd for 4 weeks. PFC were significantly increased in both malnourished and Cd-treated rats. Similar increase in PFC was observed in rats fed on Ca-D but not P-D diet containing 10 or 100 ppm of Cd. Whereas, rats fed on Ca+P-D diet containing 100 ppm of Cd exhibited a significant decrease in PFC.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
PL175-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7683362-Animals,
pubmed-meshheading:7683362-Antibody Formation,
pubmed-meshheading:7683362-Body Weight,
pubmed-meshheading:7683362-Calcium,
pubmed-meshheading:7683362-Chlordecone,
pubmed-meshheading:7683362-Hemolytic Plaque Technique,
pubmed-meshheading:7683362-Male,
pubmed-meshheading:7683362-Nutrition Disorders,
pubmed-meshheading:7683362-Organ Size,
pubmed-meshheading:7683362-Protein Deficiency,
pubmed-meshheading:7683362-Rats,
pubmed-meshheading:7683362-Rats, Sprague-Dawley,
pubmed-meshheading:7683362-Spleen
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pubmed:year |
1993
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pubmed:articleTitle |
Effects of chlordecone and malnutrition on immune response in rats.
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pubmed:affiliation |
Department of Biological Sciences, Grambling State University, Louisiana 71245.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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