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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1993-5-14
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pubmed:abstractText |
Sixty-five unselected cases of gastric cancer have been analysed for EBV DNA by polymerase chain reaction, in situ hybridization and immunohistochemistry for CD21 antigen expression. Four cases were found EBV-positive by PCR, while ISH yielded positive results in 3 of these cases, demonstrating EBV in the nuclei of cancerous cells. CD21 antigen was expressed in cancerous cells in all 3 ISH-positive cases. All the EBV-positive cancers of the present series were poorly to moderately differentiated adenocarcinomas with prominent lymphoid infiltration. These results are discussed also on the basis of the literature.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0020-7136
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
898-901
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:7682538-Adenocarcinoma,
pubmed-meshheading:7682538-Adult,
pubmed-meshheading:7682538-Aged,
pubmed-meshheading:7682538-Aged, 80 and over,
pubmed-meshheading:7682538-Base Sequence,
pubmed-meshheading:7682538-DNA, Viral,
pubmed-meshheading:7682538-Dendritic Cells,
pubmed-meshheading:7682538-Female,
pubmed-meshheading:7682538-Herpesvirus 4, Human,
pubmed-meshheading:7682538-Humans,
pubmed-meshheading:7682538-Immunohistochemistry,
pubmed-meshheading:7682538-In Situ Hybridization,
pubmed-meshheading:7682538-Lymphoid Tissue,
pubmed-meshheading:7682538-Male,
pubmed-meshheading:7682538-Microtomy,
pubmed-meshheading:7682538-Middle Aged,
pubmed-meshheading:7682538-Molecular Sequence Data,
pubmed-meshheading:7682538-Neoplasm Staging,
pubmed-meshheading:7682538-Paraffin Embedding,
pubmed-meshheading:7682538-Polymerase Chain Reaction,
pubmed-meshheading:7682538-Receptors, Complement 3d,
pubmed-meshheading:7682538-Staining and Labeling,
pubmed-meshheading:7682538-Stomach Neoplasms
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pubmed:year |
1993
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pubmed:articleTitle |
Epstein-Barr virus and gastric cancer: data and unanswered questions.
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pubmed:affiliation |
Institute of Pathologic Anatomy and Histology, University of Siena, Italy.
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pubmed:publicationType |
Journal Article
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