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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1993-4-22
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pubmed:abstractText |
An Alu polymerase chain reaction (PCR) probe specific for chromosome 11 prepared from the somatic cell hybrid J1 was used to analyze karyotypes of eight patients with acute monocytic leukemia (AML-M5). Chromosome painting confirmed the t(9;11) in one patient and a der(1)t(1;6)t(6;11) in another and allowed the identification of a complex rearrangement involving chromosomes 9, 11, and 17, previously classified as del(11)(q23), in a third patient. An analysis of five patients with AML-M5 and a normal karyotype did not detect abnormalities of chromosome 11. The usefulness of chromosome painting combined with in situ hybridization with probes previously located on particular chromosomes is emphasized.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1045-2257
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7680885-Adult,
pubmed-meshheading:7680885-Aged,
pubmed-meshheading:7680885-Aged, 80 and over,
pubmed-meshheading:7680885-Child,
pubmed-meshheading:7680885-Chromosome Aberrations,
pubmed-meshheading:7680885-Chromosome Deletion,
pubmed-meshheading:7680885-Chromosomes, Human, Pair 11,
pubmed-meshheading:7680885-Chromosomes, Human, Pair 17,
pubmed-meshheading:7680885-Chromosomes, Human, Pair 9,
pubmed-meshheading:7680885-DNA Probes,
pubmed-meshheading:7680885-Female,
pubmed-meshheading:7680885-Humans,
pubmed-meshheading:7680885-In Situ Hybridization, Fluorescence,
pubmed-meshheading:7680885-Infant,
pubmed-meshheading:7680885-Karyotyping,
pubmed-meshheading:7680885-Leukemia, Monocytic, Acute,
pubmed-meshheading:7680885-Male,
pubmed-meshheading:7680885-Middle Aged,
pubmed-meshheading:7680885-Polymerase Chain Reaction,
pubmed-meshheading:7680885-Translocation, Genetic
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pubmed:year |
1993
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pubmed:articleTitle |
Chromosome painting in acute monocytic leukemia.
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pubmed:affiliation |
INSERM U 301, Institut de Génétique Moléculaire, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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