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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1993-3-5
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pubmed:abstractText |
A phenotypic analysis of bronchoalveolar lavage fluid (BALF) and peripheral blood (PB) cells in maedi visna virus (MVV)-infected sheep has been performed. The differential cell count in BALF from MVV-infected animals was characterized by a significant increase (P < 0.05) in lymphocytes and neutrophils. Lymphocyte phenotyping in BALF from MVV-infected sheep showed a significant decrease (P < 0.05) of CD4+ cells, a significant increase (P < 0.05) of CD8+ cells and a significant inversion (P < 0.001) of the CD4+/CD8+ ratio. CD5+ lymphocytes were also significantly decreased (P < 0.05). Gamma delta T cells and B cells did not differ significantly when compared with the controls. No correlation was observed between BALF and PB lymphocyte phenotypes. BALF macrophages from MVV-infected animals showed increased MHC class II expression and BALF lymphocytes from the same animals demonstrated up-regulation of LFA-1 and LFA-3 expression. These findings and their relationship with lentiviral pathogenesis are discussed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-117729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1304726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1348546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-13584702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1466120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1570684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1651984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1675163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1692651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-1826600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2078294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2160344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2307933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2415661,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2448376,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2462499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2472238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2528463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2544657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2880724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2990087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-2998068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-3000489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-3055656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-3484719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-3894225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-3970445,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-5157932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-6226835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-6318629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-6454846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7679060-6606781
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
272-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7679060-Animals,
pubmed-meshheading:7679060-Antigens, CD,
pubmed-meshheading:7679060-Antigens, CD58,
pubmed-meshheading:7679060-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:7679060-Cell Count,
pubmed-meshheading:7679060-Female,
pubmed-meshheading:7679060-Histocompatibility Antigens Class II,
pubmed-meshheading:7679060-Lymphocyte Function-Associated Antigen-1,
pubmed-meshheading:7679060-Macrophages,
pubmed-meshheading:7679060-Membrane Glycoproteins,
pubmed-meshheading:7679060-Phenotype,
pubmed-meshheading:7679060-Pneumonia, Progressive Interstitial, of Sheep,
pubmed-meshheading:7679060-Sheep,
pubmed-meshheading:7679060-T-Lymphocytes
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pubmed:year |
1993
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pubmed:articleTitle |
Phenotypic analysis of cells in bronchoalveolar lavage fluid and peripheral blood of maedi visna-infected sheep.
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pubmed:affiliation |
Department of Veterinary Pathology, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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