Linked Life Data

7678647

Source:http://linkedlifedata.com/resource/pubmed/id/7678647

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-2-23
pubmed:abstractText
Intraperitoneal administration of 4-methylcatechol, which is one of the potent stimulators of nerve growth factor (NGF) synthesis in vitro, induced an increase in NGF protein and NGF mRNA in the adult rat heart and submaxillary gland. The increase in NGF protein was successively translocated from the sciatic nerve to sensory or sympathetic ganglia. Repetitive administration of 1,2-diacetoxypropylbenzene, an acetylated form of 4-methylcatechol analog, caused significant elevations of substance P levels in sensory ganglia and tyrosine hydroxylase activity in superior cervical ganglia of infant rats. These observations suggest that both compounds could stimulate NGF synthesis in vivo and that the induced NGF had physiological effects on peripheral neurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-3565
pubmed:author
pubmed:issnType
Print
pubmed:volume
264
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Pharmacological induction of physiologically active nerve growth factor in rat peripheral nervous system.
pubmed:affiliation
Department of Molecular Biology, Gifu Pharmaceutical University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't