Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1995-10-17
|
| pubmed:abstractText |
To determine the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) markers among Bahraini children with hereditary haemolytic anaemias, a cross-sectional study was conducted at the paediatric outpatient clinic of Sulimaniya Medical Center in the State of Bahrain. A total of 242 patients with hereditary haemolytic anaemias were enrolled in the study: 171 (71%) with sickle cell syndromes, 59 (24%) with beta thalassaemia major and 12 (5%) with alpha thalassaemia. Among the 191 multi-transfused patients, 39 (20.5%) had one or more markers for HBV, 78 (40%) were seropositive for HCV antibody, and three (1.6%) were seropositive for HIV antibody. In contrast, none of the 51 non-transfusion group was seropositive for HBV and HIV antibodies but one patient was seropositive for HCV antibody. HBV, HCV and HIV infections therefore remain a major hazard for children with hereditary haemolytic anaemias, despite blood donor screening. More refined and sensitive tests which would detect infection in all stages of the disease are required. Hepatitis B vaccine should be given to all children with hereditary haemolytic anaemias.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0272-4936
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
121-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:7677412-Adolescent,
pubmed-meshheading:7677412-Adult,
pubmed-meshheading:7677412-Anemia, Hemolytic, Congenital,
pubmed-meshheading:7677412-Antibodies, Viral,
pubmed-meshheading:7677412-Bahrain,
pubmed-meshheading:7677412-Blood Transfusion,
pubmed-meshheading:7677412-Child,
pubmed-meshheading:7677412-Child, Preschool,
pubmed-meshheading:7677412-Cross-Sectional Studies,
pubmed-meshheading:7677412-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7677412-Female,
pubmed-meshheading:7677412-HIV Infections,
pubmed-meshheading:7677412-Hepatitis B,
pubmed-meshheading:7677412-Hepatitis C,
pubmed-meshheading:7677412-Humans,
pubmed-meshheading:7677412-Infant,
pubmed-meshheading:7677412-Male,
pubmed-meshheading:7677412-Prevalence,
pubmed-meshheading:7677412-Retrospective Studies,
pubmed-meshheading:7677412-Risk Factors,
pubmed-meshheading:7677412-Seroepidemiologic Studies
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Prevalence of hepatitis B, hepatitis C and human immune deficiency virus markers among patients with hereditary haemolytic anaemias.
|
| pubmed:affiliation |
Sulmaniya Medical Center, Arabian Gulf University, Bahrain.
|
| pubmed:publicationType |
Journal Article
|