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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1995-10-13
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pubmed:abstractText |
A retrospective study of 69 cases of infective endocarditis in 68 children (group I: 1971-1981; 34 children; group II: 1982-1992; 34 children) disclosed the following features: a moderate increase in the global incidence of infective endocarditis (0.5% of children hospitalized in paediatric cardiology units) and of its incidence in the very young (proportion of children less than 1 year of age: 9% in group 1 and 17% in group II); no rheumatic heart disease amongst predisposing heart diseases in children living in France; a major causal role of congenital heart diseases (72%), with an increasing incidence of previous operation (group I: 42%; group II: 56%); an increase in associated complex congenital heart diseases (group I: 11%; group II: 20%); no change in related mitral valve prolapse (5% in both groups); positive blood cultures in 76% of cases, with similar rates of Staphylococci (group I: 27%; group II: 30%) and of unusual microorganisms (15% in both groups); a major diagnostic role for echocardiography (vegetations in group II: 64%). Complications occurred in 75% of cases in both groups (pulmonary or systemic emboli, mycotic aneurysms, valvar regurgitation), leading to heart failure in 29% of group I patients and in 32% of group II patients. Mortality has decreased, from 12% in group I to 3% in group II, as a result of more frequent cardiovascular surgery (group I: 11 cases; group II: 15 cases), problems due to restrictive prostheses, and severe consequences: only 27% of group II children were cured without deterioration of their cardiac condition.(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0195-668X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16 Suppl B
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
28-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7671921-Adolescent,
pubmed-meshheading:7671921-Age Distribution,
pubmed-meshheading:7671921-Child,
pubmed-meshheading:7671921-Child, Preschool,
pubmed-meshheading:7671921-Endocarditis, Bacterial,
pubmed-meshheading:7671921-Female,
pubmed-meshheading:7671921-Heart Diseases,
pubmed-meshheading:7671921-Humans,
pubmed-meshheading:7671921-Incidence,
pubmed-meshheading:7671921-Infant,
pubmed-meshheading:7671921-Male,
pubmed-meshheading:7671921-Postoperative Complications,
pubmed-meshheading:7671921-Prognosis,
pubmed-meshheading:7671921-Retrospective Studies
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pubmed:year |
1995
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pubmed:articleTitle |
Changing patterns and prognosis of infective endocarditis in childhood.
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pubmed:affiliation |
Hôpital Cardio-Vasculaire et Pneumologique, BP Lyon-Montchat, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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