Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-10-16
pubmed:abstractText
Nalbuphin is a new agonist-antagonist opioid, with a noteworthy ceiling-effect in terms of analgesia and respiratory depression, a proper cardiocirculatory innocuousness, so that it seems to be a safe analgesic in children. Our study reports 40 thoracic or abdominal surgical procedures, with nalbuphine 0.22 +/- 0.04 mg.kg-1 as sole analgesic. To ensure maintenance of anaesthesia, a volatile anaesthetic agent is inhaled at 1.1 +/- 0.4 MAC concentration, and vecuronium 0.08 +/- 0.05 mg.kg-1 is administered at induction. There was no evidence of haemodynamic changes, and no change in CO2 production. There was no analgesia related adverse effect, and awakening occurred promptly. This report suggests that nalbuphin is a suitable analgesic for paediatric surgery.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0007-9685
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Peroperative evaluation of nalbuphine in pediatric thoracic and abdominal surgery].
pubmed:affiliation
Département d'Anesthésiologie 1, Hôpital A. Michallon, CHU de Grenoble.
pubmed:publicationType
Journal Article, English Abstract