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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0010097,
umls-concept:C0017262,
umls-concept:C0027882,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0037949,
umls-concept:C0178587,
umls-concept:C0332120,
umls-concept:C0443199,
umls-concept:C0543482,
umls-concept:C0599295,
umls-concept:C0678558,
umls-concept:C1705964
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pubmed:issue |
3
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pubmed:dateCreated |
1995-10-19
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pubmed:abstractText |
Morphological plasticity of medium-sized spiny neurons of the striatum was examined in Long-Evans hooded rats reared in complex or individual cage environments. Rat pups, aged 28-32 days, were housed either individually in standard laboratory cages or as a group in a large toy- and object-filled environment for 30 days. The spine density on dendrites of medium-sized spiny neurons in the dorsolateral striatum was then examined using the Golgi-Cox method. Rats reared in the complex environment displayed an increase of approximately 30% in spine density relative to those reared individually. These results demonstrate experience-dependent changes in neural structure in the striatum and suggest that the mechanisms for information storage in response to experience may be more widespread in the forebrain than previously believed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1074-7427
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
217-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
1995
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pubmed:articleTitle |
Differential rearing alters spine density on medium-sized spiny neurons in the rat corpus striatum: evidence for association of morphological plasticity with early response gene expression.
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pubmed:affiliation |
Department of Biology, University of Illinois, Urbana 61801, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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