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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9 Pt 1
pubmed:dateCreated
1995-10-10
pubmed:abstractText
Cell suspensions from six Warthin's tumors (WTs) were characterized with fluorescence-labeled cell cytometry. WT lymphocyte subsets were identified with monoclonal antibodies directed against lymphocyte-associated cell antigens including T lymphocyte subsets, B lymphocytes, and natural killer (NK) cells. Results showed that T cell proportions were 58% and B cell proportions were 39%. The T cell helper:cytotoxic-suppressor ratio was 5.7:1 and the B to T cell ratio was 0.8:1. NK cells represented 1.3% of cells. When compared to peripheral blood lymphocytes (PBLs) in the same patients, statistically significant differences were noted between PBLs and WT lymphocytes in the percentage of B lymphocytes (P < .01), T cytotoxic-suppressor lymphocytes (P < .02), NK cells (P < .01), and in the ratios of B to T lymphocytes (P < .01) and T helper to T cytotoxic-suppressor lymphocytes (P < .03). Comparing these data to retrospective data on lymphocyte distribution in normal and reactive lymph nodes, the epithelial component does not appear to exert a local effect on the lymphoid component of WT.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0023-852X
pubmed:author
pubmed:issnType
Print
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
928-33
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Characterization of lymphocyte subpopulations in Warthin's tumor.
pubmed:affiliation
Division of Head and Neck Surgery, UCLA Medical Center, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.