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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-10-11
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pubmed:abstractText |
Grancalcin is a newly discovered cytosolic calcium-binding protein, belonging to the group of EF-hand proteins. Grancalcin is specifically associated with cells originating in the bone marrow. Grancalcin binds reversibly to secretory vesicles and plasma membranes in human neutrophils and might therefore play a role in the regulation of vesicle/granule exocytosis. We describe here the production of recombinant grancalcin, the generation of antibodies to the protein and the development of a specific, accurate and sensitive ELISA for the detection of human leukocytic grancalcin. This ELISA may be useful for monitoring leukocyte infiltration into tissues.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1759
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
185
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-8
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:7665891-Antibody Specificity,
pubmed-meshheading:7665891-Calcium-Binding Proteins,
pubmed-meshheading:7665891-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7665891-Humans,
pubmed-meshheading:7665891-Leukocytes, Mononuclear,
pubmed-meshheading:7665891-Neutrophils,
pubmed-meshheading:7665891-Recombinant Proteins
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pubmed:year |
1995
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pubmed:articleTitle |
An ELISA for grancalcin, a novel cytosolic calcium-binding protein present in leukocytes.
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pubmed:affiliation |
Department of Hematology, Finsen Center, Rigshospitalet afsnit L-4041, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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