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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-10-12
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pubmed:abstractText |
Accurate localization of epileptic foci is important for pre-surgical evaluation of patients with medically intractable epilepsy, and F-18 FDG PET has been proved to be a valuable method for this purpose. To examine the clinical value with interictal brain perfusion SPECT, we performed brain perfusion SPECT of Tc-99m HMPAO by means of a high resolution SPECT camera, and compared the results with F-18 FDG PET images and MRI in 10 patients with medically intractable epilepsy. In 9 of 10 patients (90%), FDG PET images showed focal hypo-metabolism in the area corresponding with the results of electroencephalography (EEG). SPECT images, however, demonstrated hypo-perfused lesions which corresponded with hypo-metabolic lesions on FDG PET images in only 6 cases (60%). Although MRI showed abnormal findings in 8 cases, the lesions were not directly related to epileptic foci in 2 cases. In conclusion, FDG PET is a valuable tool for accurate localization of epileptic foci. Brain perfusion SPECT, however, may not always be paralleled to metabolism visualized on FDG PET images.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyglucose,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorodeoxyglucose F18,
http://linkedlifedata.com/resource/pubmed/chemical/Organotechnetium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Oximes,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium Tc 99m Exametazime
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0914-7187
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
59-63
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7662491-Adolescent,
pubmed-meshheading:7662491-Adult,
pubmed-meshheading:7662491-Deoxyglucose,
pubmed-meshheading:7662491-Epilepsy,
pubmed-meshheading:7662491-Female,
pubmed-meshheading:7662491-Fluorodeoxyglucose F18,
pubmed-meshheading:7662491-Humans,
pubmed-meshheading:7662491-Magnetic Resonance Imaging,
pubmed-meshheading:7662491-Male,
pubmed-meshheading:7662491-Middle Aged,
pubmed-meshheading:7662491-Organotechnetium Compounds,
pubmed-meshheading:7662491-Oximes,
pubmed-meshheading:7662491-Technetium Tc 99m Exametazime,
pubmed-meshheading:7662491-Tomography, Emission-Computed,
pubmed-meshheading:7662491-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
1995
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pubmed:articleTitle |
Limited value of interictal brain perfusion SPECT for detection of epileptic foci: high resolution SPECT studies in comparison with FDG-PET.
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pubmed:affiliation |
Department of Radiology, Shiga University of Medical Science, Otsu, Japan.
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pubmed:publicationType |
Journal Article
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