Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-10-5
pubmed:abstractText
Argentina has an exceptionally high frequency of hemolytic-uremic syndrome (HUS). We sought to define prospectively the role of verocytotoxins (Shiga-like toxins [SLTs]) in 254 Argentinean children with grossly bloody diarrhea during spring and summer. Free fecal SLTs (I/II) and/or DNA probe-positive isolates were found in 99 (39%) of the children. During the follow-up period, HUS developed in 6 patients (4 with evidence of recent SLT infection based on stool studies); another 14 patients had some, but not all, of the abnormalities seen in typical HUS. The development of HUS or incomplete HUS in these children was significantly associated with recent SLT-Escherichia coli infection (p = 0.024). The high incidence of SLT-associated bloody diarrhea in Argentina explains, at least partially, the unusually high frequency of HUS. Our data indicate that incomplete forms of HUS may be common in patients with SLT-associated bloody diarrhea.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-3476
pubmed:author
pubmed:issnType
Print
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
364-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:7658263-Argentina, pubmed-meshheading:7658263-Bacterial Toxins, pubmed-meshheading:7658263-Blood Cell Count, pubmed-meshheading:7658263-Chi-Square Distribution, pubmed-meshheading:7658263-Child, Preschool, pubmed-meshheading:7658263-Cytotoxins, pubmed-meshheading:7658263-DNA, Bacterial, pubmed-meshheading:7658263-Diarrhea, pubmed-meshheading:7658263-Diarrhea, Infantile, pubmed-meshheading:7658263-Escherichia coli, pubmed-meshheading:7658263-Feces, pubmed-meshheading:7658263-Female, pubmed-meshheading:7658263-Hemolytic-Uremic Syndrome, pubmed-meshheading:7658263-Humans, pubmed-meshheading:7658263-Incidence, pubmed-meshheading:7658263-Infant, pubmed-meshheading:7658263-Male, pubmed-meshheading:7658263-Nucleic Acid Hybridization, pubmed-meshheading:7658263-Prospective Studies, pubmed-meshheading:7658263-Shiga Toxins
pubmed:year
1995
pubmed:articleTitle
Incomplete hemolytic-uremic syndrome in Argentinean children with bloody diarrhea.
pubmed:affiliation
Department of Pediatric Infectious Diseases, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't