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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-10-3
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pubmed:abstractText |
Epstein-Barr-associated lymphoproliferative disorders have been described as complications of immunodeficiency states including allogeneic BMT. There is, however, only one report in the English language literature of such a disorder after autografting. We report a 56-year-old man undergoing autologous BMT for CML in whom a rapidly progressive lymphoproliferative disorder showing the histology of typical post-transplant lymphoproliferative disorder with latent EBV presence developed at approximately 30 days after BMT. Therapy with corticosteroids, acyclovir and alpha-interferon was instituted and led to prompt resolution of symptoms and signs. There was no evidence of lymphoproliferative disease at 7 months after BMT. It is concluded that EBV-associated lymphoproliferative disorders may be a complication, albeit a rare one, of intensive therapy with autologous stem cell support.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0268-3369
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
639-41
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7655394-Bone Marrow Transplantation,
pubmed-meshheading:7655394-Herpesvirus 4, Human,
pubmed-meshheading:7655394-Humans,
pubmed-meshheading:7655394-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:7655394-Lymphoproliferative Disorders,
pubmed-meshheading:7655394-Male,
pubmed-meshheading:7655394-Middle Aged,
pubmed-meshheading:7655394-Transplantation, Autologous
|
pubmed:year |
1995
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pubmed:articleTitle |
Polyclonal Epstein-Barr virus-associated lymphoproliferative disorder following autografting for chronic myeloid leukemia.
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pubmed:affiliation |
Leukemia/Bone Marrow Transplantation Program of British Columbia, B.C. Cancer Agency, Vancouver General Hospital, Canada.
|
pubmed:publicationType |
Journal Article,
Case Reports
|