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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1995-10-2
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pubmed:abstractText |
We report the case of a 12-year-old boy suffering from severe low-titer cold-hemagglutinin disease with excruciating colicky abdominal pain, jaundice, and acute hemolytic anemia requiring transfusion. Cold hemagglutinins of the IgM type and a positive direct antiglobulin test, predominantly against C3d, were found. Steroid pulse therapy with 20 mg/kg body wt. methylprednisolone for 3 consecutive days was given. Abdominal pain disappeared within 12 h of the first steroid infusion and hemolysis was halted. We conclude that a therapeutic trial with steroid pulse therapy in severe low-titer cold-hemagglutinin disease is warranted.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0939-5555
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
71
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
101-2
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:7654853-Anemia, Hemolytic, Autoimmune,
pubmed-meshheading:7654853-Autoantibodies,
pubmed-meshheading:7654853-Child,
pubmed-meshheading:7654853-Complement C3d,
pubmed-meshheading:7654853-Coombs' Test,
pubmed-meshheading:7654853-Humans,
pubmed-meshheading:7654853-Immunoglobulin M,
pubmed-meshheading:7654853-Male,
pubmed-meshheading:7654853-Methylprednisolone
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pubmed:year |
1995
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pubmed:articleTitle |
Severe low-titer cold-hemagglutinin disease responsive to steroid pulse therapy.
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pubmed:affiliation |
Children's Hospital, University of Würzburg, Germany.
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pubmed:publicationType |
Journal Article,
Case Reports
|