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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-9-26
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pubmed:abstractText |
Diabetic ketoacidosis occurs more frequently in the young adult population than in any other age group. In a 3-year retrospective casenote review of all patients admitted with ketoacidosis to this hospital, we have defined the clinical characteristics of ketoacidosis in this age group. Young adults (< 25 years) had worse preceding glycaemic control (median HbA1 14.6 vs 10.1%, p = 0.0001) and more frequent episodes of ketoacidosis in the previous 5 years (3 vs 0, p = 0.0001) than older adults (> 25 years); on admission they had lower blood urea concentrations (p = 0.0001) and had a lower incidence of systolic hypotension (6% vs 32%, p = 0.007). There were fewer complications of ketoacidosis in the young adults, and the duration of hospital stay was less than that in the older age group (4 vs 8 days, p = 0.0003). Young adults were less likely to have a proven underlying infective or other organic precipitant for ketoacidosis, but were investigated and treated in a similar way to older adults. Insulin error or manipulation was identified in 42% of young adults; abnormal insulin treatment behaviour is likely to be the major cause of ketoacidosis in this age group.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0742-3071
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429-32
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:7648807-Adolescent,
pubmed-meshheading:7648807-Adult,
pubmed-meshheading:7648807-Diabetes Mellitus, Type 1,
pubmed-meshheading:7648807-Diabetic Ketoacidosis,
pubmed-meshheading:7648807-Female,
pubmed-meshheading:7648807-Hemoglobin A, Glycosylated,
pubmed-meshheading:7648807-Humans,
pubmed-meshheading:7648807-Hypotension,
pubmed-meshheading:7648807-Incidence,
pubmed-meshheading:7648807-Insulin,
pubmed-meshheading:7648807-Length of Stay,
pubmed-meshheading:7648807-Male,
pubmed-meshheading:7648807-Medication Errors,
pubmed-meshheading:7648807-Patient Compliance,
pubmed-meshheading:7648807-Retrospective Studies
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pubmed:year |
1995
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pubmed:articleTitle |
Abnormal insulin treatment behaviour: a major cause of ketoacidosis in the young adult.
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pubmed:affiliation |
Diabetes Centre, Ninewells Hospital, Dundee, Scotland.
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pubmed:publicationType |
Journal Article
|