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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-9-26
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pubmed:abstractText |
We examined the T-cell subsets in the peripheral blood, spleen and lymph nodes during the course of experimental allergic neuritis (EAN) by using two-color analysis. In the acute phase, the percentages of CD4+ major histocompatibility complex (MHC)-II+ cells and CD8+ MHC-II+ cells in the lymph nodes of EAN rats were significantly higher than in the control rats. In the recovery phase, the percentage of CD4+ CD45RC+ cells and CD8+ CD45RC+ cells in the lymph nodes in EAN rats were significantly higher than in the control rats. However, significant changes of the T-cell subsets were not detected in either the spleen or the peripheral blood during the course of EAN. These results suggest that CD4+ MHC-II+ cells, CD8+ MHC-II+ cells, CD4+ CD45RC+ cells and CD8+ CD45RC+ cells may play a role in the course of EAN. The relationship between these double staining cells and EAN is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0918-2918
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7647400-Analysis of Variance,
pubmed-meshheading:7647400-Animals,
pubmed-meshheading:7647400-Antibodies, Monoclonal,
pubmed-meshheading:7647400-CD4-Positive T-Lymphocytes,
pubmed-meshheading:7647400-CD8-Positive T-Lymphocytes,
pubmed-meshheading:7647400-Female,
pubmed-meshheading:7647400-Flow Cytometry,
pubmed-meshheading:7647400-Lymph Nodes,
pubmed-meshheading:7647400-Lymphocyte Count,
pubmed-meshheading:7647400-Major Histocompatibility Complex,
pubmed-meshheading:7647400-Neuritis, Autoimmune, Experimental,
pubmed-meshheading:7647400-Rats,
pubmed-meshheading:7647400-Rats, Inbred Lew,
pubmed-meshheading:7647400-Spleen,
pubmed-meshheading:7647400-T-Lymphocyte Subsets
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pubmed:year |
1995
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pubmed:articleTitle |
The two-color analysis of the T-lymphocyte subsets in experimental allergic neuritis in rats.
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pubmed:affiliation |
Division of Neurology, Faculty of Medicine, Tottori University, Yonago, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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